Phthalic Anhydride

Phthalic Anhydride

SCHEMBL5378960

C=CC(=O)OCC(C)O.O=C1OC(=O)c2ccccc21

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.49
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 1/20 0.41
THRB P10828 1/20 0.41
TYMS P04818 1/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPK1 P28482 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
LMNA P02545 1/20 0.37
TRPA1 O75762 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
PLA2G1B P04054 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Anhydride SCHEMBL2010624 0.92 TSHR (0.45) TSHRALDH1A1TDP1ALOX15THRB
Phthalic Anhydride SCHEMBL2008043 0.91 TSHR (0.44) TSHRALDH1A1TDP1ALOX15THRB
Phthalic Anhydride SCHEMBL28071869 0.83 ALDH1A1 (0.55) TSHRALDH1A1TDP1ALOX15THRB
Benzene SCHEMBL28092989 0.81 TSHR (0.67) TSHRALDH1A1THRBMAPK1ADRB2
Styrene SCHEMBL25312124 0.80 TSHR (0.53) TSHRALDH1A1THRBKMT2AMAPK1
Phthalic Anhydride SCHEMBL4555543 0.79 TSHR (0.59) TSHRALDH1A1TDP1ALOX15THRB
Diphenylether SCHEMBL6002228 0.79 THRB (0.54) TSHRALDH1A1TDP1THRBGLA
SCHEMBL27800525 0.79
SCHEMBL33585 0.79
SCHEMBL27821519 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211625-B2 Thermoplastic resin composition and elastomer composition KANEKA CORPORATION (JP) 2007-05-01 US disclosed
US-20040106732-A1 Thermoplastic resin composition and elastomer composition KANEKA CORPORATION (JP) 2004-06-03 US disclosed
CN-1040602-A A kind of preparation method of photocuring etchingresistant printing material WUXI CHEMICAL RESEARCH AND DES (CN) 1990-03-21 CN disclosed