Phthalic Acid

Phthalic Acid

SCHEMBL301414

C=CC(=O)OCCO.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.63
THRB P10828 2/20 0.57
ALDH1A1 P00352 7/20 0.47
ALOX15 P16050 1/20 0.47
TP53 P04637 2/20 0.44
HIF1A Q16665 2/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KMT2A Q03164 2/20 0.44
PTK2B Q14289 1/20 0.44
KDM4E B2RXH2 4/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.39
AKR1C3 P42330 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL29430009 1.00 TSHR (0.63) TSHRTHRBALDH1A1ALOX15TP53
Phthalic Acid SCHEMBL28239002 0.91 ALDH1A1 (0.56) TSHRTHRBALDH1A1ALOX15TP53
Phthalic Acid SCHEMBL6295376 0.90 THRB (0.54) TSHRTHRBALDH1A1ALOX15TP53
Benzene SCHEMBL11756759 0.86 TSHR (0.86) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL67527 0.85 THRB (0.59) TSHRTHRBALDH1A1ALOX15TP53
SCHEMBL30198617 0.85 THRB (0.59) TSHRTHRBALDH1A1ALOX15TP53
Phthalic Acid SCHEMBL6831159 0.85 THRB (0.55) TSHRTHRBALDH1A1ALOX15TP53
SCHEMBL29906120 0.85 TSHR (0.61) TSHRTHRBALDH1A1TP53HIF1A
SCHEMBL301415 0.85 TSHR (0.61) TSHRTHRBALDH1A1TP53HIF1A
Acrylic Acid SCHEMBL864539 0.84 ALDH1A1 (0.53) TSHRALDH1A1ALOX15TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170037275-A1 HOOF REPAIR COATING DM HEALTHCARE PRODUCTS, INC 2017-02-09 US claimed
EP-1477848-B1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORP (JP) 2012-12-05 EP claimed
EP-1710021-B1 Method of forming a film by directing droplets of a liquid composition to a substrate HUNTSMAN ADV MAT SWITZERLAND (CH) 2009-03-25 EP claimed
US-7141355-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-11-28 US claimed
US-6855746-B2 Process for the production of molded particles for enzyme- or microbial cell-immobilization KANSAI PAINT CO., LTD. (JP) 2005-02-15 US claimed
US-20030100636-A1 Process for the production of molded particles for enzyme- or microbial cell-immobilization KANSAI PAINT CO., LTD. (JP) 2003-05-29 US claimed
US-5461087-A An ultraviolet curable adhesive comprising an acrylic acid ester of an alkyl alcohol and monofunctional oligoester acrylate; adhesion strength, low glass transition temperature SONY CORPORATION (JP) 1995-10-24 US claimed
US-12624140-B2 Composition containing compound having polyoxyalkylene chain RESONAC CORPORATION (JP) 2026-05-12 US disclosed
US-12624141-B2 Composition set containing compound having polyoxyalkylene chain RESONAC CORPORATION (JP) 2026-05-12 US disclosed
US-20250368766-A1 RESIN, RESIN DISPERSION, AND RESIN COMPOSITION DNP FINE CHEMICALS CO., LTD. (JP) 2025-12-04 US disclosed
US-20250346702-A1 COMPOSITION THAT CONTAINS COMPOUND HAVING POLYOXYALKYLENE CHAIN AND ACRYLIC COPOLYMER RESONAC CORP (JP) 2025-11-13 US disclosed
US-20250297092-A1 COMPOSITION THAT CONTAINS COMPOUND HAVING POLYOXYALKYLENE CHAIN AND ESTER-BASED THIXOTROPY-IMPARTING AGENT RESONAC CORPORATION (JP) 2025-09-25 US disclosed
US-20250282116-A1 SHEET COMPRISING THERMAL INSULATION LAYER AND ADHESIVE LAYER RESONAC CORPORATION (JP) 2025-09-11 US disclosed
EP-0936233-A2 Composition for a resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-08-18 EP disclosed
EP-0928802-A2 Process for tinting a resin having a large refractivity index and optical material tinted by the process MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-07-14 EP disclosed
EP-0921417-A2 Epoxy/episulfide resin compositions for optical materials MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-06-09 EP disclosed
EP-0726162-B1 High gloss printing sheet OJI PAPER CO (JP) 1998-05-13 EP disclosed
EP-0793406-A1 Process for producing multilayer wiring boards TOKYO OHKA KOGYO CO., LTD. (JP) 1997-09-03 EP disclosed
EP-0726162-A1 High gloss printing sheet NEW OJI PAPER CO., LTD. (JP) 1996-08-14 EP disclosed
US-5461087-A An ultraviolet curable adhesive comprising an acrylic acid ester of an alkyl alcohol and monofunctional oligoester acrylate; adhesion strength, low glass transition temperature SONY CORPORATION (JP) 1995-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037275-A1 HOOF REPAIR COATING UNG, OGFOD1, UTRN TSHR 2651/4885THRB 4298/4885ALDH1A1 1281/4885
US-12624140-B2 Composition containing compound having polyoxyalkylene chain PIEZO1, HVCN1, TAF11 TSHR 3431/4885THRB 908/4885ALDH1A1 1149/4885
US-12624141-B2 Composition set containing compound having polyoxyalkylene chain SET, SETD1B, SETDB1 TSHR 3995/4885THRB 2256/4885ALDH1A1 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.