Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308848 | 0.72 | THRA (0.39) | PARP1PARP15PARP10 | |
| SCHEMBL29883233 | 0.71 | — | — | |
| SCHEMBL51838 | 0.71 | — | — | |
| SCHEMBL1666449 | 0.71 | — | — | |
| SCHEMBL3295484 | 0.71 | — | — | |
| SCHEMBL14216712 | 0.70 | — | — | |
| SCHEMBL28501013 | 0.69 | GABRP (0.41) | PARP1PARP15PARP10 | |
| SCHEMBL1144247 | 0.66 | THRB (0.38) | — | |
| SCHEMBL4857880 | 0.65 | — | — | |
| SCHEMBL17235754 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501539-B2 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH SA (CH) | 2009-03-10 | — | — | US | disclosed |
| US-7501539-B2 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH SA (CH) | 2009-03-10 | — | — | US | disclosed |
| US-20050187299-A1 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH S.A. (CH) | 2005-08-25 | — | — | US | disclosed |
| US-20050187299-A1 | Process for the preparation of alkylidenecyclopentanone derivatives | FIRMENICH S.A. (CH) | 2005-08-25 | — | — | US | disclosed |
| EP-1562888-A1 | A PROCESS FOR THE PREPARATION OF ALKYLIDENECYCLOPENTANONE DERIVATIVES | FIRMENICH SA (CH) | 2005-08-17 | — | — | EP | disclosed |
| EP-1562888-A1 | A PROCESS FOR THE PREPARATION OF ALKYLIDENECYCLOPENTANONE DERIVATIVES | FIRMENICH SA (CH) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043895-A1 | A PROCESS FOR THE PREPARATION OF ALKYLIDENECYCLOPENTANONE DERIVATIVES | FIRMENICH SA (CH) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043895-A1 | A PROCESS FOR THE PREPARATION OF ALKYLIDENECYCLOPENTANONE DERIVATIVES | FIRMENICH SA (CH) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187299-A1 | Process for the preparation of alkylidenecyclopentanone derivatives | CYP1B1, AKR1C3, CYP1A1 | PARP1 276/4885PARP15 442/4885PARP10 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.