SCHEMBL1144247

SCHEMBL1144247

C=C(C(=O)O)C1CCCC(=O)C1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28177772 0.80 THRB (0.42) THRBCYP3A4CYP2C9CYP2C19
SCHEMBL3934728 0.79 THRB (0.42) THRBCYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL535720 0.79 THRB (0.42) THRBCYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL15043867 0.79 THRB (0.42) THRBCYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7893827 0.77 THRB (0.43) THRBCYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL19871212 0.76 THRB (0.40) THRBCYP2C19MAPT
SCHEMBL20278647 0.76 THRB (0.40) THRBCYP2C19MAPT
SCHEMBL14104952 0.76 THRB (0.40) THRBCYP2C19MAPT
SCHEMBL4962068 0.74
SCHEMBL399595 0.74 CES2 (0.46) SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592622-B2 Polymerizable fluorine-containing compound CENTRAL GLASS COMPANY, LIMITED (JP) 2013-11-26 US disclosed
US-8513457-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2013-08-20 US disclosed
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-09-06 US disclosed
US-8187787-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-05-29 US disclosed
US-20110098500-A1 Polymerizable Fluorine-Containing Compound CENTRAL GLASS COMPANY, LIMITED (JP) 2011-04-28 US disclosed
US-7906269-B2 Positive-type resist composition CENTRAL GLASS COMPANY, LIMITED (JP) 2011-03-15 US disclosed
US-7887990-B2 Fluorine-containing compound, fluorine-containing polymer, postive-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-02-15 US disclosed
US-20090061353-A1 Positive-Type Resist Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2009-03-05 US disclosed
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-08 US disclosed
US-20080311507-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Postive-Type Resist Composition, And Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098500-A1 Polymerizable Fluorine-Containing Compound FRG1, AFF1, H1-2 THRB 1971/4885CYP3A4 2621/4885CYP2C9 2422/4885
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same RTF1, FGFR2, FGFR1 THRB 2938/4885CYP3A4 4235/4885CYP2C9 4107/4885
US-20080311507-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Postive-Type Resist Composition, And Patterning Process Using Same FRG1, FBXL19, FEM1B THRB 1932/4885CYP3A4 3696/4885CYP2C9 2615/4885
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same FGFR2, RTF1, ADGRF1 THRB 3425/4885CYP3A4 4448/4885CYP2C9 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.