Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 8/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555727 | 0.90 | FLT3 (0.52) | NTRK1NTRK2FLT3CDK2MEN1 | |
| SCHEMBL4555775 | 0.89 | NTRK1 (0.51) | NTRK1NTRK2FLT3CDK2MEN1 | |
| SCHEMBL27796823 | 0.87 | NTRK1 (0.62) | NTRK1NTRK2FLT3CDK2MEN1 | |
| SCHEMBL4555728 | 0.86 | FLT3 (0.55) | NTRK1NTRK2FLT3CDK2MEN1 | |
| SCHEMBL2814428 | 0.82 | KMT2A (0.60) | MEN1KMT2AMAPTSMN1; SMN2NR1H4 | |
| SCHEMBL4555774 | 0.82 | NTRK1 (0.51) | NTRK1NTRK2FLT3CDK2MEN1 | |
| SCHEMBL4556337 | 0.81 | NPC1 (0.56) | MEN1KMT2ASMN1; SMN2NR1H4 | |
| SCHEMBL4556085 | 0.80 | DHPS (0.52) | MEN1KMT2AMAPTSMN1; SMN2NR1H4 | |
| SCHEMBL27775869 | 0.79 | NTRK1 (0.60) | NTRK1NTRK2FLT3MEN1KMT2A | |
| SCHEMBL4446449 | 0.79 | PIN1 (0.54) | MEN1KMT2AMAPTSMN1; SMN2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |