Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555750 | 1.00 | MAOA (0.44) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL3399289 | 0.90 | MAOA (0.41) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL3399293 | 0.90 | MAOA (0.41) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL3393120 | 0.83 | SLC6A4 (0.54) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL3393119 | 0.83 | SLC6A4 (0.54) | MAOAMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL4758034 | 0.72 | OPRK1 (0.46) | KDM4E | |
| SCHEMBL4758033 | 0.72 | OPRK1 (0.46) | KDM4E | |
| SCHEMBL20958347 | 0.71 | SLC6A2 (0.50) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20958343 | 0.71 | SLC6A2 (0.50) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20958345 | 0.71 | SLC6A2 (0.50) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121678-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074798-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2008-06-26 | — | — | WO | disclosed |