Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20958345 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A3NAAAMAPTSMN1; SMN2 | |
| SCHEMBL20958343 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A3NAAAMAPTSMN1; SMN2 | |
| SCHEMBL4758033 | 0.89 | OPRK1 (0.46) | SLC6A2SLC6A3OPRK1KCNH2 | |
| SCHEMBL4758034 | 0.89 | OPRK1 (0.46) | SLC6A2SLC6A3OPRK1KCNH2 | |
| SCHEMBL4757061 | 0.86 | OPRK1 (0.44) | SLC6A2SLC6A3OPRK1KCNH2 | |
| SCHEMBL14860921 | 0.86 | SLC6A2 (0.47) | SLC6A2SLC6A3EPHX2OPRK1KCNH2 | |
| SCHEMBL1164697 | 0.86 | ALDH1A1 (0.48) | SLC6A2SLC6A3MAPTEPHX2OPRK1 | |
| SCHEMBL1164698 | 0.86 | ALDH1A1 (0.48) | SLC6A2SLC6A3MAPTEPHX2OPRK1 | |
| SCHEMBL20958387 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A3NAAAEPHX2OPRK1 | |
| SCHEMBL12077422 | 0.86 | SLC6A2 (0.63) | SLC6A2SLC6A3NAAAEPHX2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865194-B2 | Therapeutically active bicyclic-sulphonamides and pharmaceutical compositions | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2020-12-15 | — | — | US | disclosed |
| US-20190135778-A1 | THERAPEUTICALLY ACTIVE BICYCLIC-SULPHONAMIDES AND PHARMACEUTICAL COMPOSITIONS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135778-A1 | THERAPEUTICALLY ACTIVE BICYCLIC-SULPHONAMIDES AND PHARMACEUTICAL COMPOSITIONS | NAAA, FAAH, FAAH2 | SLC6A2 2292/4885SLC6A3 2457/4885NAAA 1/4885 |
| US-10865194-B2 | Therapeutically active bicyclic-sulphonamides and pharmaceutical compositions | NAAA, FAAH2, FAAH | SLC6A2 3106/4885SLC6A3 2971/4885NAAA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.