Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555840 | 0.97 | EPHX2 (0.41) | EPHX2NR1H4PPARGALDH1A1HDAC3 | |
| SCHEMBL4555966 | 0.95 | EPHX2 (0.39) | EPHX2NR1H4PPARGALDH1A1HDAC3 | |
| SCHEMBL2820070 | 0.85 | ALDH1A1 (0.48) | EPHX2NR1H4PPARGALDH1A1HDAC3 | |
| SCHEMBL4556271 | 0.84 | PKM (0.46) | EPHX2NR1H4ALDH1A1HTTSYK | |
| SCHEMBL4555841 | 0.82 | PPARG (0.38) | PPARGHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4556270 | 0.78 | MEN1 (0.45) | NR1H4ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4556269 | 0.75 | PLAU (0.47) | NR1H4ALDH1A1AAK1TNIKKDM4E | |
| SCHEMBL4438564 | 0.72 | PKM (0.46) | NR1H4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27796830 | 0.72 | MAPT (0.46) | NR1H4ALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL4556044 | 0.71 | NR1H4 (0.49) | EPHX2NR1H4ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | claimed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | claimed |