Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556349 | 1.00 | ADAM17 (0.50) | ADAM17MMP12MMP2 | |
| SCHEMBL4059802 | 1.00 | ADAM17 (0.50) | ADAM17MMP12MMP2 | |
| SCHEMBL6681651 | 0.89 | MMP12 (0.47) | ADAM17MMP12MMP2 | |
| SCHEMBL4056893 | 0.87 | MMP12 (0.60) | ADAM17MMP12MMP2 | |
| SCHEMBL4050014 | 0.86 | MMP13 (0.59) | ADAM17MMP12MMP2 | |
| SCHEMBL4053664 | 0.85 | MMP12 (0.61) | ADAM17MMP12MMP2 | |
| SCHEMBL4053393 | 0.85 | MMP2 (0.59) | ADAM17MMP2 | |
| SCHEMBL4051465 | 0.85 | MMP2 (0.60) | ADAM17MMP12MMP2 | |
| SCHEMBL4056527 | 0.84 | ADAM17 (0.55) | ADAM17MMP2 | |
| SCHEMBL4053799 | 0.83 | MMP13 (0.55) | ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | claimed |