Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.34 |
| ▸ | HRH1 | P35367 | 5/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026480 | 0.79 | MEN1 (0.32) | HTR2AHRH1RETHTR2C | |
| SCHEMBL2169848 | 0.77 | HTR1A (0.39) | HTR2AHRH1RETHTR2CADRA1B | |
| SCHEMBL4310302 | 0.75 | HTR2A (0.33) | HTR2AHRH1RETHTR2CPRCP | |
| SCHEMBL458495 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2CPRCP | |
| SCHEMBL4290508 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2CPRCP | |
| SCHEMBL6521360 | 0.75 | HTR2A (0.35) | HTR2AHRH1HTR2CPRCP | |
| SCHEMBL3389204 | 0.72 | HTR2A (0.35) | HTR2AHRH1RETHTR2C | |
| SCHEMBL8890669 | 0.72 | CHRNB2 (0.33) | HTR2A | |
| SCHEMBL458123 | 0.71 | HTR2A (0.34) | HTR2AHRH1RETHTR2C | |
| SCHEMBL4307808 | 0.71 | HTR2A (0.34) | HTR2AHRH1RETHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| WO-2009136965-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | SEQUELLA, INC. (US) | 2009-11-12 | — | — | WO | disclosed |