Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19920065 | 0.85 | POLB (0.47) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL6657928 | 0.85 | POLB (0.47) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL11073553 | 0.84 | LMNA (0.46) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6409959 | 0.83 | POLB (0.46) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL7181205 | 0.83 | POLB (0.46) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL11077027 | 0.83 | POLB (0.66) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL17755257 | 0.81 | POLB (0.51) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL23256418 | 0.81 | EPHX1 (0.58) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL5160804 | 0.79 | PDE4A (0.49) | POLBL3MBTL1HTTNPSR1LMNA | |
| SCHEMBL14678302 | 0.79 | L3MBTL1 (0.53) | POLBL3MBTL1HTTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | POLB 2126/4885L3MBTL1 1826/4885HTT 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.