Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873403 | 0.79 | UMPS (0.39) | TSHRLMNAMAPTPMP22SMN1; SMN2 | |
| SCHEMBL7623585 | 0.69 | LMNA (0.32) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631190 | 0.66 | TSHR (0.40) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL29423327 | 0.63 | UMPS (0.39) | — | |
| SCHEMBL30751087 | 0.63 | SLC5A2 (0.40) | — | |
| SCHEMBL29510865 | 0.63 | UMPS (0.39) | — | |
| SCHEMBL16631575 | 0.63 | TSHR (0.37) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16021207 | 0.61 | KDM3B (0.38) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL31565646 | 0.61 | PYGM (0.41) | LMNA | |
| SCHEMBL29286002 | 0.61 | UMPS (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129094-A2 | COMPOSITIONS CONTAINING ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | WO | disclosed |