Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911229 | 0.80 | CA12 (0.43) | ALDH1A1HIF1ALMNATDP1HSD17B10 | |
| SCHEMBL26325 | 0.77 | TSHR (0.48) | ALDH1A1HIF1ATSHRLMNATDP1 | |
| SCHEMBL28021555 | 0.76 | HSD17B10 (0.47) | ALDH1A1HIF1ATDP1HSD17B10PTPRC | |
| SCHEMBL57963 | 0.75 | HSD17B10 (0.50) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL16005234 | 0.75 | TSHR (0.46) | ALDH1A1HIF1ATSHRLMNATDP1 | |
| SCHEMBL3591508 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL1473759 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL887743 | 0.75 | TSHR (0.48) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL455697 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| Water SCHEMBL28995322 | 0.75 | TSHR (0.46) | ALDH1A1HIF1ATSHRLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295162-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | SEMMELWEIS EGYETEM (HU) | 2023-09-21 | — | — | US | claimed |
| CN-116437925-A | Synthesis of novel elmidone derivatives and evaluation of anticancer activity thereof | 厄特沃什罗兰科技大学 | 2023-07-14 | — | — | CN | claimed |
| EP-4192467-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | Eötvös Loránd Tudományegyetem (HU) | 2023-06-14 | — | — | EP | claimed |
| CN-110734391-B | 2, 3-diketone indole compound and preparation method and application thereof | 山东大学 | 2023-05-02 | — | — | CN | claimed |
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-112110846-A | N-aryl phthalimide derivative and preparation method and application thereof | 河北农业大学 | 2020-12-22 | — | — | CN | claimed |
| CN-110734391-A | 2, 3-diketone indole compound and preparation method and application thereof | 山东大学 | 2020-01-31 | — | — | CN | claimed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | claimed |
| EP-2532663-B1 | Naphthalenetetracarboxylic acid derivatives and their use as semiconductors | BASF SE (DE) | 2016-03-16 | — | — | EP | claimed |
| WO-2006127587-A1 | PYRROLOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-11-30 | — | — | WO | claimed |
| WO-2006105289-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | claimed |
| US-20060223810-A1 | Bicyclic pyrazole compounds as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | claimed |
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2005-09-01 | — | — | US | claimed |
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | claimed |
| EP-0594047-B1 | Arylazo chromoionophores | BAYER AG (US) | 2000-01-05 | — | — | EP | claimed |
| US-5473058-A | A maltooligosaccharide attached to a dye, preferably resorufin or a halonitro phenol; a substrate in the presence of salivary alpha-amylase | BOEHRINGER MANNHEIM GMBH (DE) | 1995-12-05 | — | — | US | claimed |
| US-5470715-A | Composition for determination of chloride ion | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1995-11-28 | — | — | US | claimed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | claimed |
| EP-0594047-A1 | Arylazo chromoionophores | Bayer Corporation (US) | 1994-04-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295162-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | IMPA1, REN, IGF1R | ALDH1A1 38/4885HIF1A 3234/4885TSHR 1686/4885 |
| US-20060223810-A1 | Bicyclic pyrazole compounds as antibacterial agents | NOD2, BAK1, CASP3 | ALDH1A1 3885/4885HIF1A 3603/4885TSHR 4510/4885 |
| US-20050192324-A1 | Novel dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | DPP4, DPP3, DPP7 | ALDH1A1 1221/4885HIF1A 3939/4885TSHR 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.