P-Xylene

P-Xylene

SCHEMBL4557367

Cc1ccc(C)cc1.O=C(O)C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of P-Xylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
LMNA P02545 4/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
TDP1 Q9NUW8 4/20 0.57
ACHE P22303 2/20 0.57
SRD5A2 P31213 1/20 0.55
HTT P42858 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
KMT2A Q03164 3/20 0.50
PKM P14618 2/20 0.50
ATM Q13315 2/20 0.50
HPGD P15428 2/20 0.50
MEN1 O00255 2/20 0.50
NLRP1 Q9C000 1/20 0.50
GAA P10253 1/20 0.50
NTSR1 P30989 1/20 0.50
CTBP2 P56545 1/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL27538150 0.89 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Xylene SCHEMBL14721484 0.89 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Cresol SCHEMBL27919457 0.88 ACHE (0.72) ALDH1A1SMN1; SMN2LMNACES2CES1
Toluene SCHEMBL29210074 0.87 LMNA (0.69) ALDH1A1SMN1; SMN2LMNACES2CES1
Toluene SCHEMBL29210071 0.87 LMNA (0.69) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Xylene SCHEMBL28594820 0.86 CES2 (0.56) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Xylene SCHEMBL2595392 0.86 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Xylene SCHEMBL28442305 0.84 ACHE (0.80) ALDH1A1SMN1; SMN2LMNACES2CES1
P-Xylene SCHEMBL28696945 0.84 ACHE (0.80) ALDH1A1SMN1; SMN2LMNACES2CES1
Toluene SCHEMBL28230148 0.84 LMNA (0.65) ALDH1A1SMN1; SMN2LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11764321-B2 Backsheet comprising a polyolefine based functional layer facing the back encapsulant ENDURANCE SOLAR SOLUTIONS B.V. (NL) 2023-09-19 US disclosed
US-20220033679-A1 BACKSHEET FOR PHOTOVOLTAIC MODULES COMPRISING AN ALIPHATIC POLYAMIDE ENDURANCE SOLAR SOLUTIONS B.V. (NL) 2022-02-03 US disclosed
EP-3857614-A1 BACKSHEET FOR PHOTOVOLTAIC MODULES COMPRISING AN ALIPHATIC POLYAMIDE DSM Advanced Solar B.V. (NL) 2021-08-04 EP disclosed
EP-3539162-B1 BACKSHEET COMPRISING A POLYOLEFINE BASED FUNCTIONAL LAYER FACING THE BACK ENCAPSULANT DSM ADVANCED SOLAR B V (NL) 2021-07-21 EP disclosed
US-20210151617-A1 NIR-REFLECTIVE MULTI-LAYER MATERIAL SHEET ENDURANCE SOLAR SOLUTIONS INC. 2021-05-20 US disclosed
EP-3821471-A1 NIR-REFLECTIVE MULTI-LAYER MATERIAL SHEET DSM IP Assets B.V. (NL) 2021-05-19 EP disclosed
CN-112385050-A Near infrared reflective multilayer material sheet 帝斯曼知识产权资产管理有限公司 2021-02-19 CN disclosed
WO-2020064858-A1 BACKSHEET FOR PHOTOVOLTAIC MODULES COMPRISING AN ALIPHATIC POLYAMIDE DSM IP ASSETS B.V. (NL) 2020-04-02 WO disclosed
US-20190296167-A1 BACKSHEET COMPRISING A POLYOLEFINE BASED FUNCTIONAL LAYER FACING THE BACK ENCAPSULANT ENDURANCE SOLAR SOLUTIONS INC. 2019-09-26 US disclosed
EP-3539162-A1 BACKSHEET COMPRISING A POLYOLEFINE BASED FUNCTIONAL LAYER FACING THE BACK ENCAPSULANT DSM IP Assets B.V. (NL) 2019-09-18 EP disclosed
EP-0542875-B1 THERMOPLASTIC COMPOSITION CONTAINING AN ISOOLEFIN-PARA-ALKYLSTYRENE COPOLYMER ADVANCED ELASTOMER SYSTEMS (US) 1995-10-18 EP disclosed
EP-0337976-B1 High temperature stable, low solvent swelling thermoplastic elastomer compositions ADVANCED ELASTOMER SYSTEMS (US) 1994-06-22 EP disclosed
US-5300573-A High temperature stable, low solvent swelling thermoplastic elastomer compositions ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1994-04-05 US disclosed
EP-0542875-A1 THERMOPLASTIC COMPOSITION CONTAINING AN ISOOLEFIN-PARA-ALKYLSTYRENE COPOLYMER. ADVANCED ELASTOMER SYSTEMS (US) 1993-05-26 EP disclosed
WO-1992002582-A1 THERMOPLASTIC COMPOSITION CONTAINING AN ISOOLEFIN-PARA-ALKYLSTYRENE COPOLYMER ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1992-02-20 WO disclosed
EP-0337976-A2 High temperature stable, low solvent swelling thermoplastic elastomer compositions ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1989-10-18 EP disclosed
EP-0032123-B1 MONO-OLEFIN POLYMERS HAVING METHYLOL PHENOLIC GROUPS GRAFTED THERETO, A PROCESS FOR THEIR PRODUCTION AND POLYMER BLENDS CONTAINING THEM MONSANTO COMPANY (US) 1984-05-16 EP disclosed
EP-0032123-A2 Mono-olefin polymers having methylol phenolic groups grafted thereto, a process for their production and polymer blends containing them MONSANTO COMPANY (US) 1981-07-15 EP disclosed
US-4278572-A Phenolic modified olefin polymers MONSANTO COMPANY (US) 1981-07-14 US disclosed
US-4141863-A CROSSLINKED MONSANTO COMPANY (US) 1979-02-27 US disclosed