Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413939 | 0.86 | MAPT (0.59) | DYRK1AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL8368151 | 0.85 | MAPT (0.58) | DYRK1AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL30683712 | 0.83 | SMN1; SMN2 (0.57) | NPC1RAB9AMAPK1LMNAALDH1A1 | |
| SCHEMBL8860019 | 0.80 | MKNK1 (0.57) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL28059172 | 0.79 | RAB9A (0.62) | DYRK1AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL12906820 | 0.79 | RAB9A (0.52) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL27386699 | 0.78 | IKBKB (0.47) | DYRK1ALMNACSNK2A1MAP4K4TNIK | |
| SCHEMBL28059182 | 0.76 | DYRK1A (0.54) | DYRK1AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1143140 | 0.76 | DYRK1A (1.00) | DYRK1AMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL5838154 | 0.76 | RAB9A (0.67) | DYRK1AMAPTNPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091832-A1 | SYNTHESIS OF PYRAZOLES | WYETH (US) | 2009-07-23 | — | — | WO | disclosed |