Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69492 | 0.85 | MEN1 (0.58) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1221862 | 0.84 | MEN1 (0.57) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8860019 | 0.83 | MKNK1 (0.57) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30683712 | 0.83 | SMN1; SMN2 (0.57) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3417205 | 0.82 | CYP3A4 (0.55) | ALDH1A1HPGDS | |
| SCHEMBL12882360 | 0.82 | RAB9A (0.52) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5935124 | 0.82 | RAB9A (0.52) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13539265 | 0.79 | RAB9A (0.49) | RAB9APOLBNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4557695 | 0.79 | DYRK1A (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2ALPL | |
| SCHEMBL975662 | 0.79 | KIF11 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-108713019-A | Active 5- ethyls -4- methyl pyrazole -3- carboxamides derivatives with the agonist as TAAR | 豪夫迈·罗氏有限公司 | 2018-10-26 | — | — | CN | disclosed |
| WO-2011016559-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |