SCHEMBL4557966

SCHEMBL4557966

C=CCNC(=O)/C=C\C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 4/20 0.46
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
RAB9A P51151 3/20 0.42
NPC1 O15118 1/20 0.42
KMT2A Q03164 1/20 0.41
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
HPGD P15428 2/20 0.40
DDAH1 O94760 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 1/20 0.38
FAAH O00519 1/20 0.36
FGFR4 P22455 1/20 0.36
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9281803 1.00 ALDH1A1 (0.46) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL5482541 1.00 ALDH1A1 (0.46) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL6435438 0.89 SMN1; SMN2 (0.52) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL6435439 0.89 SMN1; SMN2 (0.52) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL4318714 0.80 ALDH1A1 (0.46) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL239953 0.80 ALDH1A1 (0.46) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL239954 0.80 ALDH1A1 (0.46) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
Acrylamide SCHEMBL9362700 0.80 ALDH1A1 (0.52) ALDH1A1TSHRMAPTSMN1; SMN2RAB9A
SCHEMBL307121 0.76
SCHEMBL10499492 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070275869-A1 Polysaccharide Derivatives, Their Production and Use BIOGHURT BIOGARDE GMBH & CO., KG (DE) 2007-11-29 US claimed
US-8399551-B2 Functionalized elastomer nanocomposite EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-03-19 US disclosed
EP-1527127-B1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE EXXONMOBIL CHEM PATENTS INC (US) 2009-02-11 EP disclosed
US-20070275869-A1 Polysaccharide Derivatives, Their Production and Use BIOGHURT BIOGARDE GMBH & CO., KG (DE) 2007-11-29 US disclosed
US-20060100339-A1 Functionalized elastomer nanocomposite EXXON MOBIL CHEMICAL PATENTS INC. (US) 2006-05-11 US disclosed
EP-1527127-A1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE Exxonmobil Chemical Patents Inc. (US) 2005-05-04 EP disclosed
WO-2004005388-A1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-15 WO disclosed
US-20020119171-A1 COPOLYMERIC HYDROPHOBICALLY MODIFIED POLYASPARTIC ESTER AMIDES AND THEIR USE GOLDSCHMIDT AG (DE) 2002-08-29 US disclosed
EP-0787157-B1 OLEAGINOUS COMPOSITIONS COMPRISING GRAFTED ISOMONOOLEFIN ALKYLSTYRENE POLYMERS INFINEUM USA LP (US) 2000-12-20 EP disclosed
US-5700871-A HEAT AND OZONE RESISTANCE; OIL REPELLENTS EXXON CHEMICAL PATENTS INC. (US) 1997-12-23 US disclosed
EP-0582588-A1 GRAFTED POLYMERS OF AN ISOMONOOLEFIN AND AN ALKYLSTYRENE. EXXON CHEMICAL PATENTS INC (US) 1994-02-16 EP disclosed
US-5238990-A Blended with graft polymers of isomonoolefin, p-alkylstyrene, unsaturated acids or derivatives EXXON CHEMICAL PATENTS INC. (US) 1993-08-24 US disclosed
WO-1992021722-A1 HIGH MODULUS TOUGHENED POLYAMIDE COMPOSITION EXXON CHEMICAL PATENTS INC. (US) 1992-12-10 WO disclosed
WO-1992016569-A1 GRAFTED POLYMERS OF AN ISOMONOOLEFIN AND AN ALKYLSTYRENE EXXON CHEMICAL PATENTS INC. (US) 1992-10-01 WO disclosed
EP-0155567-B1 LIGHT-TRANSMITTING FIBER MITSUBISHI RAYON CO., LTD. (JP) 1991-12-04 EP disclosed
US-5032403-A Transdermal dryg delivery CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4693553-A Light-transmitting fiber MITSUBISHI RAYON COMPANY LTD. (JP) 1987-09-15 US disclosed
EP-0155567-A2 Light-transmitting fiber MITSUBISHI RAYON CO., LTD. (JP) 1985-09-25 EP disclosed
US-4464506-A COPOLYMER OF VINYL ORGANOSILOXANE, SI-H GROUP ORGANOSILOXANE, AND ADDITIONAL MONOMER BAYER AKTIENGESELLSCHAFT (DE) 1984-08-07 US disclosed
US-4463127-A Crosslinkable graft polymer dispersion of organopolysiloxanes containing hydrogen-siloxane groups and Si-vinyl groups BAYER AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119171-A1 COPOLYMERIC HYDROPHOBICALLY MODIFIED POLYASPARTIC ESTER AMIDES AND THEIR USE ARGLU1, ARG1, SLC7A1 ALDH1A1 3048/4885TSHR 1380/4885MAPT 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.