SCHEMBL4558007

SCHEMBL4558007

O=C(NCCCN(CCCCN(CCCNC(=O)c1cccc(O)c1O)C(=O)c1cccc(=O)n1O)C(=O)c1cccc(=O)n1O)c1cccc(O)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.53
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NLRP1 Q9C000 1/20 0.41
IDH1 O75874 1/20 0.40
NAAA Q02083 1/20 0.38
MMP1 P03956 1/20 0.37
MMP3 P08254 1/20 0.37
MMP7 P09237 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37
NAMPT P43490 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13531452 0.87 IDH1 (0.50) NPC1ALDH1A1HPGDTSHRHSD17B10
SCHEMBL15118460 0.84 LIPG (0.49) ALOX5IDH1MMP1MMP3MMP7
SCHEMBL19577100 0.83 LIPG (0.48) ALOX5IDH1MMP1MMP3MMP7
SCHEMBL31679432 0.83 ALOX5 (0.68) ALOX5NPC1ALDH1A1MAPTHPGD
SCHEMBL19943815 0.83 ALOX5 (0.68) ALOX5NPC1ALDH1A1MAPTHPGD
SCHEMBL7612287 0.82 ALOX5 (0.70) ALOX5NPC1ALDH1A1MAPTHPGD
SCHEMBL13074649 0.81 ALOX5 (0.51) ALOX5NPC1ALDH1A1MAPTHPGD
SCHEMBL24636658 0.80 IDH1 (0.43) ALDH1A1HPGDTSHRHSD17B10IDH1
SCHEMBL24452602 0.78 IDH1 (0.41) ALDH1A1MAPTHPGDTSHRHSD17B10
SCHEMBL20026898 0.77 ALOX5 (0.58) ALOX5NPC1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2074240-A2 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS Nalco Company (US) 2009-07-01 EP disclosed
WO-2008060782-A2 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS NALCO COMPANY (US) 2008-05-22 WO disclosed
US-20080083435-A1 METHOD OF INHIBITING CORROSION IN STORAGE AND TRANSPORT VESSELS ECOLAB USA INC. 2008-04-10 US disclosed