Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | TOP2A | P11388 | 9/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217009 | 0.88 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL500386 | 0.88 | ALDH1A1 (0.66) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL29962586 | 0.88 | ALDH1A1 (0.66) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6171288 | 0.86 | TOP2A (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Fluoride SCHEMBL5143354 | 0.86 | ALDH1A1 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL5143359 | 0.85 | ALDH1A1 (0.62) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL4476600 | 0.84 | ADRB2 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Fluoride SCHEMBL6169863 | 0.84 | TOP2A (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9149649 | 0.83 | TOP2A (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6171004 | 0.83 | TOP2A (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9746770-B2 | Thermally developable imaging materials and methods | CARESTREAM HEALTH, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9523915-B2 | Image forming materials, preparations, and compositions | CARESTREAM HEALTH, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160357104-A1 | THERMALLY DEVELOPABLE IMAGING MATERIALS AND METHODS | CARESTREAM HEALTH WORLD HOLDINGS LLC | 2016-12-08 | — | — | US | disclosed |
| US-9335623-B2 | Thermally developable imaging materials | CARESTREAM HEALTH, INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-20160124306-A1 | IMAGE FORMING MATERIALS, PREPARATIONS, AND COMPOSITIONS | CARESTREAM HEALTH WORLD HOLDINGS LLC | 2016-05-05 | — | — | US | disclosed |
| US-20150268550-A1 | THERMALLY DEVELOPABLE IMAGING MATERIALS | CARESTREAM HEALTH ACQUISITION, LLC | 2015-09-24 | — | — | US | disclosed |
| US-7514206-B2 | Thermally developable materials with buried conductive backside coatings | CARESTREAM HEALTH, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-7482454-B2 | Antimicrobial quinolones, their compositions, and uses | THE PROCTER & GAMBLE COMPANY (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1910895-B1 | THERMALLY DEVELOPABLE MATERIALS WITH ABRASION-RESISTANT BACKSIDE COATINGS | CARESTREAM HEALTH INC (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7371709-B2 | Thermally developable materials with backside antistatic layer | TROPHY DENTAL INC. | 2008-05-13 | — | — | US | disclosed |
| US-7097963-B1 | Halogen substituted tetraazaindene compounds in photothermographic materials | EASTMAN KODAK COMPANY (US) | 2006-08-29 | — | — | US | disclosed |
| US-20060141402-A1 | Aqueous-based photothermographic materials containing tetrafluoroborate salts | EASTMAN KODAK COMPANY | 2006-06-29 | — | — | US | disclosed |
| US-20060141403-A1 | Blocked aliphatic thiol stabilizers for photothermographic materials | EASTMAN KODAK COMPANY | 2006-06-29 | — | — | US | disclosed |
| US-20060100436-A1 | Antimicrobial quinolones, their compositions, and uses | WARNER CHILCOTT COMPANY, LLC | 2006-05-11 | — | — | US | disclosed |
| CN-1671690-A | Antimicrobial azabicyclic derivatives, compositions and uses thereof | PROCTER & GAMBLE (US) | 2005-09-21 | — | — | CN | disclosed |
| US-6900224-B2 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1532137-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2004-02-26 | — | — | US | disclosed |
| WO-2004014893-A2 | ANTIMICROBIAL AZA-BICYCLIC DERIVATES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-19 | — | — | WO | disclosed |
| US-6329391-B1 | ANTIBIOTICS, BACTERICIDES USING QUINOLONES | THE PROCTER & GAMBLE CO. | 2001-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100436-A1 | Antimicrobial quinolones, their compositions, and uses | Q6ZSR9, RECQL, QARS1 | ALDH1A1 2880/4885POLB 1857/4885OPRM1 1801/4885 |
| US-20040038975-A1 | Antimicrobial quinolones, their compositions and uses | QARS1, NQO2, Q6ZSR9 | ALDH1A1 2739/4885POLB 210/4885OPRM1 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.