Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6926710 | 0.99 | ALDH1A1 (0.49) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL6470512 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL518233 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL4862025 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL4558508 | 0.78 | SLC6A2 (0.53) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2236360 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL6472114 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL2432523 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL2432094 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRGLASLC6A2SLC6A4 | |
| SCHEMBL1415853 | 0.75 | SLC6A4 (0.56) | ALDH1A1TSHRGLASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | ALDH1A1 2069/4885TSHR 271/4885GLA 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.