Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913174 | 0.82 | RIPK1 (0.44) | ALDH1A1MEN1KMT2APOLBRIPK1 | |
| SCHEMBL518233 | 0.81 | ALDH1A1 (0.53) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL6470512 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL4862025 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL4558508 | 0.77 | SLC6A2 (0.53) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL5538599 | 0.76 | ALDH1A1 (0.50) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6926710 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL2432523 | 0.74 | ALDH1A1 (0.51) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL2432094 | 0.74 | ALDH1A1 (0.51) | ALDH1A1GLATSHRSLC6A2SLC6A4 | |
| SCHEMBL2595399 | 0.73 | TSHR (0.62) | ALDH1A1GLATSHRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | ALDH1A1 2036/4885GLA 4584/4885TSHR 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.