Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326205 | 0.78 | L3MBTL1 (0.36) | SLC6A4L3MBTL1KDM4EHSD17B10TDP1 | |
| SCHEMBL3470484 | 0.73 | MEN1 (0.37) | CYP2D6L3MBTL1HSD17B10 | |
| SCHEMBL21994346 | 0.72 | KDM1A (0.40) | SLC6A2SLC6A4SLC6A3L3MBTL1CYP2A6 | |
| SCHEMBL28231919 | 0.72 | ERBB2 (0.35) | ACHEKDM4EHSD17B10 | |
| SCHEMBL7849802 | 0.72 | KDM4E (0.41) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| Naphthalene SCHEMBL27590915 | 0.71 | CYP2B6 (0.40) | ACHEBCHEMAOBKDM4ETDP1 | |
| SCHEMBL28806765 | 0.71 | ALDH1A1 (0.34) | L3MBTL1CYP2A6HSD17B10TDP1 | |
| SCHEMBL2466948 | 0.71 | — | — | |
| Ethylene SCHEMBL27830648 | 0.71 | MEN1 (0.35) | — | |
| SCHEMBL20472624 | 0.71 | CYP1A2 (0.41) | ACHEL3MBTL1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111463352-A | Organic light emitting device and display apparatus including the same | 三星显示有限公司 | 2020-07-28 | — | — | CN | claimed |
| US-7498349-B2 | Biaryl compounds having anti-infective activity | GENESOFT PHARMACEUTICALS, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1539151-A4 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS INC (US) | 2006-10-11 | — | — | EP | disclosed |
| US-20060128747-A1 | Biaryl compounds having anti-infective activity | GENESOFT PHARMACEUTICALS,INC. (US) | 2006-06-15 | — | — | US | disclosed |
| EP-1539151-A1 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | Genesoft Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004012736-A1 | BIARYL COMPOUNDS HAVING ANTI-INFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS, INC. (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128747-A1 | Biaryl compounds having anti-infective activity | LSS, BET1, TYR | ACHE 1228/4885BCHE 930/4885CHRNB2 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.