Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616969 | 0.82 | LMNA (0.39) | SLC6A2SLC6A4SLC6A3TSHRNPSR1 | |
| SCHEMBL6160196 | 0.77 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL11800360 | 0.77 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL253431 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL21742323 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL4759333 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL4954290 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL10945061 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL11034374 | 0.73 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 | |
| SCHEMBL1385556 | 0.73 | SLC6A3 (0.45) | SLC6A2SLC6A4SLC6A3TSHRKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233893-A1 | Methods of Dissolving Beta-Sheet Proteins and Uses Thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2009-09-17 | — | — | US | disclosed |
| WO-2007139805-A2 | METHODS OF DISSOLVING BETA-SHEET PROTEINS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233893-A1 | Methods of Dissolving Beta-Sheet Proteins and Uses Thereof | CACYBP, HSPBP1, SLC30A7 | SLC6A2 2924/4885SLC6A4 3280/4885SLC6A3 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.