Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068058 | 1.00 | PTPN22 (0.52) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL29362162 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL29418178 | 0.87 | ALDH1A1 (0.56) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL15400598 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL455943 | 0.87 | ALDH1A1 (0.56) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL29027 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL28432478 | 0.87 | THRB (0.45) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL30267558 | 0.87 | THRB (0.45) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL30267536 | 0.86 | ESR2 (0.52) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL28425968 | 0.86 | ESR2 (0.52) | PTPN22HDAC3IDO1EP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535329-B | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2024-09-17 | — | — | CN | claimed |
| CN-117946169-A | Axis chiral binaphthyl phosphite skeleton tridentate P, N, N-ligand, preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-04-30 | — | — | CN | claimed |
| CN-116536430-A | SNP molecular marker related to fear behaviors and/or separation anxiety behaviors of dogs and application thereof | 云南大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116535329-A | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2023-08-04 | — | — | CN | claimed |
| CN-110551036-B | Iridium/chiral phosphite ester-pyridine catalyzed imine asymmetric hydrogenation method | 中国科学院大连化学物理研究所 | 2022-04-12 | — | — | CN | claimed |
| CN-112920072-B | NOBIN biaryl compound and synthetic method thereof | 山东大学 | 2022-03-15 | — | — | CN | claimed |
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | SPHENOTECH CO., LIMITED (CN) | 2025-07-17 | — | — | US | disclosed |
| WO-2025094700-A1 | TRIFLUOROMETHANESULFONATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND | 学校法人神戸薬科大学 | 2025-05-08 | — | — | WO | disclosed |
| CN-119775170-A | Preparation method of sabatier starter intermediate | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119059883-A | Method for copper-catalyzed dynamic racemization of chiral biaryl compound of chiral quaternary ammonium salt co-crystallization induced shaft | 复旦大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-116535329-B | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-116535329-B | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-116535329-B | Synthetic method of NOBIN-type axial chiral biaryl compound and compound thereof | 湖南师范大学 | 2024-09-17 | — | — | CN | disclosed |
| WO-2022101627-A1 | METHOD OF SYNTHESIS | UNIVERSITY OF DURHAM (GB) | 2022-05-19 | — | — | WO | disclosed |
| CN-112961037-B | Method for resolving racemic chiral compound by molecular distillation method | 浙江工业大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110551036-B | Iridium/chiral phosphite ester-pyridine catalyzed imine asymmetric hydrogenation method | 中国科学院大连化学物理研究所 | 2022-04-12 | — | — | CN | disclosed |
| CN-112920072-B | NOBIN biaryl compound and synthetic method thereof | 山东大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-112920072-B | NOBIN biaryl compound and synthetic method thereof | 山东大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-112920072-B | NOBIN biaryl compound and synthetic method thereof | 山东大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-111233932-B | Chiral phosphoric acid with spiro indane skeleton and preparation method and application thereof | 南方科技大学 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | PKD1, PKD2, SYMPK | PTPN22 1502/4885HDAC3 3120/4885IDO1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.