Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364830 | 1.00 | PTPN22 (0.52) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL29362162 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL29418178 | 0.87 | ALDH1A1 (0.56) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL15400598 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL455943 | 0.87 | ALDH1A1 (0.56) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL29027 | 0.87 | PTPN22 (0.65) | PTPN22IDO1MAPTALDH1A1KDM4E | |
| SCHEMBL28432478 | 0.87 | THRB (0.45) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL30267558 | 0.87 | THRB (0.45) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL30267536 | 0.86 | ESR2 (0.52) | PTPN22HDAC3IDO1EP300KAT2B | |
| SCHEMBL28425968 | 0.86 | ESR2 (0.52) | PTPN22HDAC3IDO1EP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382779-A | One planting sand storehouse must bent intermediate preparation method | 江苏中邦制药有限公司 | 2017-11-24 | — | — | CN | claimed |
| US-6864347-B2 | Nonlinear optical chiral compounds and devices incorporating same | KVH INDUSTRIES, INC. (US) | 2005-03-08 | — | — | US | claimed |
| WO-2003099746-A1 | METHOD FOR THE PRODUCTION OF 18F-FLUORINATED ALPHA ACIDS | ABX GMBH (DE) | 2003-12-04 | — | — | WO | claimed |
| US-20030161605-A1 | Nonlinear optical chiral compounds and devices incorporating same | KVH INDUSTRIES, INC. | 2003-08-28 | — | — | US | claimed |
| WO-2003003112-A1 | NONLINEAR OPTICAL CHIRAL COMPOUNDS AND DEVICES INCORPORATING SAME | KVH INDUSTRIES, INC. (US) | 2003-01-09 | — | — | WO | claimed |
| WO-2001000581-A1 | LIGANDS BASED ON CHIRAL 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL AND RELATED FRAMEWORKS FOR ASYMMETRIC CATALYSIS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-01-04 | — | — | WO | claimed |
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | SPHENOTECH CO., LIMITED (CN) | 2025-07-17 | — | — | US | disclosed |
| US-20240025839-A1 | METHOD OF SYNTHESIS | UNIVERSITY OF DURHAM (GB) | 2024-01-25 | — | — | US | disclosed |
| EP-3169430-B1 | NEW ULTRAHIGH EFFICIENCY, SUPERFICIALLY POROUS PARTICLE (SPP) CHIRAL PHASES FOR LIQUID CHROMATOGRAPHY | AZYP LLC (US) | 2021-11-10 | — | — | EP | disclosed |
| US-20210238200-A1 | CHIRAL N-SUBSTITUTED ALLYLIC AMINE COMPOUNDS | UNIVERSITY OF LOUISIANA AT LAFAYETTE | 2021-08-05 | — | — | US | disclosed |
| US-11021494-B2 | Chiral N-substituted allylic amine compounds | UNIVERSITY OF LOUISIANA AT LAFAYETTE (US) | 2021-06-01 | — | — | US | disclosed |
| CN-107814729-B | A kind of chirality aromatic amine compounds and preparation method thereof | 中国科学技术大学 | 2019-11-22 | — | — | CN | disclosed |
| US-10272364-B2 | Superficially porous particle (SPP) chiral phases for liquid chromatography | AZYP, LLC (US) | 2019-04-30 | — | — | US | disclosed |
| WO-2001000581-A1 | LIGANDS BASED ON CHIRAL 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL AND RELATED FRAMEWORKS FOR ASYMMETRIC CATALYSIS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000581-A1 | LIGANDS BASED ON CHIRAL 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL AND RELATED FRAMEWORKS FOR ASYMMETRIC CATALYSIS | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-01-04 | — | — | WO | disclosed |
| JP-2000191676-A | PRODUCTION OF OPTICALLY ACTIVE AMINOPHOSPHINE COMPOUND | TAKASAGO INTERNATL CORP | 2000-07-11 | — | — | JP | disclosed |
| EP-1013658-A1 | Aminophosphine-metal complex for asymmetric reactions | Takasago International Corporation (JP) | 2000-06-28 | — | — | EP | disclosed |
| CN-1255490-A | Optical decomposing process of 2-amino-2'-hydroxyl-1,1'-dinaphthalene | UNIV ZHENGZHOU (CN) | 2000-06-07 | — | — | CN | disclosed |
| CN-1255490-A | Optical decomposing process of 2-amino-2'-hydroxyl-1,1'-dinaphthalene | UNIV ZHENGZHOU (CN) | 2000-06-07 | — | — | CN | disclosed |
| US-5599963-A | Catalysts for production of β-hydroxy carbonyl compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025839-A1 | METHOD OF SYNTHESIS | NIT2, NAA15, ASNS | PTPN22 881/4885HDAC3 1315/4885IDO1 1107/4885 |
| US-20210238200-A1 | CHIRAL N-SUBSTITUTED ALLYLIC AMINE COMPOUNDS | HNMT, NNMT, PNMT | PTPN22 2886/4885HDAC3 1565/4885IDO1 251/4885 |
| US-11021494-B2 | Chiral N-substituted allylic amine compounds | HNMT, NNMT, PNMT | PTPN22 2712/4885HDAC3 1457/4885IDO1 289/4885 |
| US-20250229262-A1 | CHIRAL SPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF | PKD1, PKD2, SYMPK | PTPN22 1502/4885HDAC3 3120/4885IDO1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.