SCHEMBL8914968

SCHEMBL8914968

CCC(C)(CC)c1cc(Cn2c(=O)[nH]c(=O)[nH]c2=O)cc(C(C)(CC)CC)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.38
MAPT P10636 7/20 0.38
KDM4E B2RXH2 5/20 0.38
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
THRB P10828 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 5/20 0.34
TSHR P16473 4/20 0.34
LMNA P02545 2/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456005 0.87 ALDH1A1 (0.49) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL7604116 0.85 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL14472121 0.78 TDP1 (0.46) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL7631700 0.75 MAOA (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL698535 0.75 ALDH1A1 (0.49) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL7601523 0.74 THRB (0.42) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL8755484 0.73 GAA (0.39) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL28529861 0.72 GAA (0.44) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL7601716 0.72 ALDH1A1 (0.44) ALDH1A1MAPTKDM4ETDP1MEN1
SCHEMBL21694100 0.70 GAA (0.44) ALDH1A1MAPTKDM4ETDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624982-A BENZOTRIAZOLE COMPOUNDS FOR LIGHT STABILIZERS OF TETRAMETHYL PIPERIDINYL SEBACATE FOR STYRENE POLYMERS BAYER ANTWERPEN SA/NV (BE) 1997-04-29 US disclosed
EP-0736064-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN N.V. (BE) 1996-10-09 EP disclosed
US-5492948-A STABILIZER FOR STYRENE POLYMERS CONSISTING OF A BENZOTRIAZOLE, OLIGOMERIC CONDENSATE OF 2,4-DICHLORO-6-MORPHOLINO-S-TRIAZINE AND N,N*-/2,2,6,6-TETRAMETHYLPIPERIDYL/HEXAMETHYLENEDIAMINE, TRIS/3,5-DI-TERT-BUTYL-4-HYDROXYBENZYL/ ISOCYANURATE MONSANTO COMPANY (US) 1996-02-20 US disclosed
WO-1995015358-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN SA/NV (BE) 1995-06-08 WO disclosed