Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20513152 | 0.86 | NPC1 (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL26102021 | 0.82 | DGAT1 (0.47) | LPLLIPG | |
| SCHEMBL30392753 | 0.82 | DGAT1 (0.47) | LPLLIPG | |
| SCHEMBL9927901 | 0.81 | LIPG (0.52) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL17548453 | 0.81 | LPL (0.47) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL19471858 | 0.80 | LIPG (0.44) | LPLLIPG | |
| SCHEMBL31353257 | 0.79 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL31353381 | 0.79 | LPL (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL17355532 | 0.79 | LIPG (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL228212 | 0.78 | LPL (0.71) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| EP-2614063-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER IP GMBH (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-9139494-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139494-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| US-20130338133-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-12-19 | — | — | US | disclosed |
| US-8580404-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580404-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| US-20130001538-A1 | Triphenylene Hosts in Phosphorescent Light Emitting Diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130001538-A1 | Triphenylene Hosts in Phosphorescent Light Emitting Diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |
| US-20120032156-A1 | Triphenylene Hosts in Phosphorescent Light Emitting Diodes | UNIVERSAL DISPLAY CORPORATION | 2012-02-09 | — | — | US | disclosed |
| US-20120032156-A1 | Triphenylene Hosts in Phosphorescent Light Emitting Diodes | UNIVERSAL DISPLAY CORPORATION | 2012-02-09 | — | — | US | disclosed |
| US-8092924-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2012-01-10 | — | — | US | disclosed |
| US-8092924-B2 | Triphenylene hosts in phosphorescent light emitting diodes | UNIVERSAL DISPLAY CORPORATION (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2277978-A2 | Triphenylene hosts in phosphorescent light emitting diodes | Universal Display Corporation (US) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338133-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BUB1, TTBK1, BUB1B | LPL 4193/4885LIPG 2189/4885CA1 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.