Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826430 | 0.78 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL20443883 | 0.78 | ADRA1A (0.45) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL1512796 | 0.78 | PIM1 (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL29987655 | 0.78 | PIM1 (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL10302847 | 0.76 | ADRB2 (0.43) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL19466332 | 0.72 | ADRA2A (0.33) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL17429416 | 0.72 | TSHR (0.53) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL12787049 | 0.70 | ADRB2 (0.39) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL17355559 | 0.70 | KDM1A (0.36) | — | |
| SCHEMBL10302844 | 0.69 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168081-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8114310-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-7854970-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20100301270-A1 | LIQUID-CRYSTALLINE MEDUIM | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100304049-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-7807068-B2 | reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays | MERCK PATENT GESELLSCHAFT (DE) | 2010-10-05 | — | — | US | disclosed |
| US-7803434-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-7767280-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7731865-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20100051864-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7560147-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2009-07-14 | — | — | US | disclosed |
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090103011-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2009-04-23 | — | — | US | disclosed |
| US-7425355-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20080197319-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080191166-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080193681-A1 | Liquid-Crystal Medium | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080191167-A1 | Liquid-crystalline medium | MERCK PATENT GMBH | 2008-08-14 | — | — | US | disclosed |
| US-7371437-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-7335403-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090141215-A1 | POLYMERIZABLE COMPOUNDS | VCL, LCP1, LPXN | ADRA2A 4617/4885ADRA2B 4751/4885ADRA2C 4455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.