Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320741 | 0.82 | TSHR (0.34) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL27476590 | 0.74 | TDP1 (0.40) | — | |
| SCHEMBL1416218 | 0.73 | KDM4E (0.30) | TSHRKDM4E | |
| SCHEMBL561780 | 0.72 | TSHR (0.34) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL821284 | 0.72 | TSHR (0.34) | TSHRSMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL462909 | 0.71 | TSHR (0.34) | TSHRKDM4EALDH1A1 | |
| SCHEMBL462908 | 0.71 | TSHR (0.34) | TSHRKDM4EALDH1A1 | |
| SCHEMBL8982707 | 0.70 | — | — | |
| SCHEMBL465931 | 0.70 | — | — | |
| SCHEMBL465932 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869092-A1 | HYDROPHILIC CORE POLYMERIC MICELLES FOR THE DELIVERY OF WATER-SOLUBLE COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2007-12-26 | — | — | EP | claimed |
| WO-2006105659-A1 | HYDROPHILIC CORE POLYMERIC MICELLES FOR THE DELIVERY OF WATER-SOLUBLE COMPOUNDS | Université de Montréal (CA) | 2006-10-12 | — | — | WO | claimed |
| US-20090214605-A1 | Hydrophilic Core Polymeric Micelles for the Delivery of Water-Soluble Compounds | DE MONTREAL, UNIVERSITE (CA) | 2009-08-27 | — | — | US | disclosed |
| EP-1869092-A1 | HYDROPHILIC CORE POLYMERIC MICELLES FOR THE DELIVERY OF WATER-SOLUBLE COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105659-A1 | HYDROPHILIC CORE POLYMERIC MICELLES FOR THE DELIVERY OF WATER-SOLUBLE COMPOUNDS | Université de Montréal (CA) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214605-A1 | Hydrophilic Core Polymeric Micelles for the Delivery of Water-Soluble Compounds | ABCB4, PAM, PGR | TSHR 1633/4885SMN1; SMN2 3644/4885MAPT 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.