SCHEMBL456377

SCHEMBL456377

CP(=O)(O)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
TSHR P16473 2/20 0.48
FDPS P14324 1/20 0.47
LAP3 P28838 4/20 0.45
ANPEP P15144 3/20 0.45
ACP3 P15309 1/20 0.44
CFTR P13569 1/20 0.43
ERAP1 Q9NZ08 2/20 0.42
ALDH1A1 P00352 1/20 0.42
ERAP2 Q6P179 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA5A P35218 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11296695 0.87 ENPP2 (0.45) HPGDFDPSCA2
SCHEMBL497159 0.80 HPGD (0.60) HPGDTSHRFDPSLAP3ANPEP
SCHEMBL8890450 0.80 HPGD (0.54) HPGDTSHRFDPS
Benzylphosphonic Acid SCHEMBL44318 0.80 HPGD (0.60) HPGDTSHRLAP3ANPEPACP3
SCHEMBL9972116 0.80 HPGD (0.54) HPGDTSHRFDPSLAP3ANPEP
SCHEMBL18392888 0.79 LMNA (0.48) HPGDTSHR
Benzylphosphonic Acid SCHEMBL10975289 0.79 HPGD (0.54) HPGDLAP3ANPEPACP3
SCHEMBL17004009 0.78 HPGD (0.58) HPGDTSHRFDPSLAP3ANPEP
Benzylphosphonic Acid SCHEMBL11474641 0.78 HPGD (0.58) HPGDTSHRLAP3ANPEPACP3
SCHEMBL6310521 0.78 HPGD (0.58) HPGDTSHRFDPSLAP3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2026-04-09 US claimed
CN-113518803-B Waterproof property of organic external wall 罗门哈斯公司 2023-09-15 CN claimed
EP-3941982-B1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2023-06-21 EP claimed
US-20220154010-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM AND HAAS COMPANY (US) 2022-05-19 US claimed
EP-3941982-A1 WATER RESISTANCE FOR ORGANIC FACADES Rohm and Haas Company (US) 2022-01-26 EP claimed
CN-113518803-A Water resistance of organic outer wall 罗门哈斯公司 2021-10-19 CN claimed
WO-2020197825-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM AND HAAS COMPANY (US) 2020-10-01 WO claimed
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2026-04-09 US disclosed
US-12516149-B2 Flame retardant epoxy resin composition TORAY INDUSTRIES, INC. (JP) 2026-01-06 US disclosed
US-12435222-B2 Water resistance for organic facades ROHM AND HAAS COMPANY (US) 2025-10-07 US disclosed
EP-4359478-B1 SYSTEMS AND METHODS FOR COATING MULTI-LAYERED COATED METAL SUBSTRATES PRC DESOTO INT INC (US) 2025-08-06 EP disclosed
US-12221554-B2 Electrodepositable coating composition PRC-DESOTO INTERNATIONAL, INC. (US) 2025-02-11 US disclosed
CN-119192231-A Hydroxyl-containing organic phosphonate and preparation method and application thereof 威海海润新材料科技有限公司 2024-12-27 CN disclosed
US-4537923-A CURING CATALYSTS FOR ACID-CURABLE RESINS CIBA GEIGY CORPORATION (US) 1985-08-27 US disclosed
EP-0055216-B1 PROCESS FOR CURING STOVE ENAMELS CIBA-GEIGY AG (CH) 1984-09-19 EP disclosed
US-4429077-A PIPERIDINE SALT AS CURING AGENT CIBA-GEIGY CORPORATION (US) 1984-01-31 US disclosed
EP-0097616-A1 Polyalkylpiperidine esters of sulfonic acids CIBA-GEIGY AG (CH) 1984-01-04 EP disclosed
EP-0055216-A1 Process for curing stove enamels CIBA-GEIGY AG (CH) 1982-06-30 EP disclosed
US-4168267-A Phosphinylalkanoyl prolines E. R. SQUIBB & SONS, INC. (US) 1979-09-18 US disclosed
US-4069247-A Preparation of phosphonic and/or phosphinic acids HOECHST AKTIENGESELLSCHAFT (DT) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ERG, LATS2, FTO HPGD 3228/4885TSHR 1930/4885FDPS 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.