SCHEMBL4564262

SCHEMBL4564262

CS(=O)(=O)CCNC(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
LMNA P02545 1/20 0.59
POLB P06746 1/20 0.59
NAAA Q02083 1/20 0.56
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18049985 0.85 SMN1; SMN2 (0.54) L3MBTL1GAASMN1; SMN2
SCHEMBL10282273 0.84 LMNA (0.62) L3MBTL1LMNAPOLBGAASMN1; SMN2
SCHEMBL5709109 0.84 L3MBTL1 (0.60) L3MBTL1LMNAPOLBNAAAGAA
SCHEMBL5638909 0.83 EPHX2 (0.57) POLB
SCHEMBL31185928 0.83 NPC1 (0.54) L3MBTL1LMNASMN1; SMN2
SCHEMBL31186198 0.83 CYP1A2 (0.50) LMNAPOLB
SCHEMBL3101975 0.83 LOXL2 (0.43) L3MBTL1LMNAPOLBSMN1; SMN2
SCHEMBL31185802 0.83 CYP1A2 (0.60) L3MBTL1LMNAGAASMN1; SMN2
SCHEMBL19755858 0.82 SMN1; SMN2 (0.54) L3MBTL1GAASMN1; SMN2
SCHEMBL668703 0.82 L3MBTL1 (0.59) L3MBTL1LMNAPOLBGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709384-A2 COMBINATION THERAPY FOR TREATMENT OF CANCER PMV Pharmaceuticals, Inc. (US) 2026-03-18 EP disclosed
WO-2024238404-A2 COMBINATION THERAPY FOR TREATMENT OF CANCER PMV PHARMACEUTICALS, INC. (US) 2024-11-21 WO disclosed
CN-118851960-A Synthesis method of N- (2- (methylsulfonyl) ethyl) amide compound 南昌大学 2024-10-29 CN disclosed
EP-3205642-B1 ANILINE INTERMEDIATE FOR THE PREPARATION OF AN AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE. MITSUI CHEMICALS AGRO INC (JP) 2022-03-23 EP disclosed
CN-105732414-B The method of control of amide derivatives, the noxious organism control agent containing the amide derivatives and harmful organism 三井化学AGRO株式会社 2019-05-03 CN disclosed
CN-105061251-B Anil 三井化学AGRO株式会社 2019-04-19 CN disclosed
EP-2593426-A1 1-HYDROXYIMINO-3-PHENYL-PROPANES F.HOFFMANN-LA ROCHE AG (CH) 2013-05-22 EP disclosed
WO-2012007365-A1 1-HYDROXYIMINO-3-PHENYL-PROPANES F. HOFFMANN-LA ROCHE AG (CH) 2012-01-19 WO disclosed
EP-2121637-A1 ANTHRANILAMIDE INHIBITORS OF AURORA KINASE Smithkline Beecham Corporation (US) 2009-11-25 EP disclosed
WO-2008092049-A1 ANTHRANILAMIDE INHIBITORS OF AURORA KINASE SMITHKLINE BEECHAM CORPORATION (US) 2008-07-31 WO disclosed
EP-0339976-B1 Anti-tumour agents ICI PLC (GB) 1994-02-02 EP disclosed
US-5238962-A Administering an antidepressants HOFFMANN-LA ROCHE INC. (US) 1993-08-24 US disclosed
EP-0339976-A1 Anti-tumour agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-02 EP disclosed