Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709109 | 0.84 | L3MBTL1 (0.60) | L3MBTL1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL28284128 | 0.83 | CA1 (0.59) | GAACA1CA2NPC1RAB9A | |
| SCHEMBL4564262 | 0.82 | L3MBTL1 (0.59) | L3MBTL1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL10248310 | 0.82 | HPGDS (0.59) | L3MBTL1SMN1; SMN2CA1CA2MEN1 | |
| SCHEMBL11343355 | 0.81 | MAPT (0.66) | L3MBTL1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL3192014 | 0.80 | LMNA (0.77) | GAASMN1; SMN2LMNAPOLBCA1 | |
| SCHEMBL10035679 | 0.78 | HPGD (0.56) | L3MBTL1SMN1; SMN2LMNAPOLBNPC1 | |
| SCHEMBL10624683 | 0.78 | L3MBTL1 (0.55) | L3MBTL1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL2168052 | 0.77 | HDAC1 (0.63) | L3MBTL1GAASMN1; SMN2LMNAPOLB | |
| SCHEMBL731620 | 0.77 | CYP1A2 (0.67) | GAASMN1; SMN2LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606038-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024373-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |