Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449528 | 0.77 | — | — | |
| SCHEMBL27797451 | 0.68 | — | — | |
| SCHEMBL7514813 | 0.62 | ALDH1A1 (0.56) | VCAM1 | |
| SCHEMBL29702010 | 0.62 | ALDH1A1 (0.56) | VCAM1 | |
| SCHEMBL306305 | 0.60 | P2RX7 (0.42) | VCAM1 | |
| SCHEMBL9139396 | 0.58 | TSHR (0.46) | VCAM1 | |
| Alcohol SCHEMBL27912165 | 0.57 | TDP1 (0.48) | VCAM1 | |
| SCHEMBL10980919 | 0.57 | TSHR (0.62) | VCAM1 | |
| SCHEMBL9422167 | 0.57 | ALDH1A1 (0.50) | VCAM1 | |
| SCHEMBL10455740 | 0.57 | GPR35 (0.48) | VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124562-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008112205-A1 | BICYCLOHETEROARYL COMPOUNDS AS P2X7 MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |