Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575260 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL487677 | 0.86 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL9062213 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL10950262 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL6380240 | 0.80 | MEN1 (0.44) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL2162561 | 0.78 | GABRA1 (0.50) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL721648 | 0.75 | GABRA1 (0.52) | — | |
| SCHEMBL8112329 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4956920 | 0.75 | HPGD (0.56) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL608187 | 0.74 | WDR5 (0.50) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948712-B1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2012-12-26 | — | — | EP | disclosed |
| US-7528212-B2 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-05-05 | — | — | US | disclosed |
| EP-1948712-A2 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007061672-A2 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117957-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-24 | — | — | US | disclosed |