Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950262 | 0.86 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL27326726 | 0.85 | CNR1 (0.44) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL897607 | 0.84 | KDM4E (0.55) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| Ammonia Solution, Strong SCHEMBL7720474 | 0.82 | KDM4E (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| Ammonia Solution, Strong SCHEMBL7720478 | 0.82 | KDM4E (0.53) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28189392 | 0.82 | MAPK8 (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8878945 | 0.81 | NCEH1 (0.40) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4564431 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL5039098 | 0.79 | ATM (0.40) | ALDH1A1HPGDHSD17B10NCEH1TDP1 | |
| SCHEMBL10051639 | 0.78 | CDC25B (0.54) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549615-A1 | NAPHTHAMIDE DERIVATIVES AND THEIR USE | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004020411-A1 | NAPHTHAMIDE DERIVATIVES AND THEIR USE | ASTRAZENECA AB (SE) | 2004-03-11 | — | — | WO | disclosed |