SCHEMBL4564491

SCHEMBL4564491

CC1=C(C)C(C)C([Ti](=[SiH]Cc2ccccc2)C2=C(C)C(C)=C(C)C2C)=C1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7639447 0.98 LMNA (0.33) LMNAPOLB
SCHEMBL7031405 0.72 MAOB (0.37) ACHE
SCHEMBL7035387 0.70 MAOA (0.35) ACHE
SCHEMBL9064177 0.68 TP53 (0.34) LMNAPOLBACHE
SCHEMBL9064078 0.68
Hydrochloric Acid SCHEMBL4467798 0.67 ACHE (0.33) LMNAPOLBACHE
Hydrochloric Acid SCHEMBL4477638 0.67 MEN1 (0.31)
Hydrochloric Acid SCHEMBL4885097 0.67
SCHEMBL9244022 0.65 CALM1 (0.42) LMNAPOLB
SCHEMBL3690826 0.65 CALM1 (0.42) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945471-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU KOSAN CO (JP) 2009-05-13 EP disclosed