Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.54 |
| ▸ | PRKCA | P17252 | 10/20 | 0.52 |
| ▸ | PRKACA | P17612 | 3/20 | 0.52 |
| ▸ | PRKACG | P22612 | 3/20 | 0.52 |
| ▸ | PRKACB | P22694 | 3/20 | 0.52 |
| ▸ | PIM1 | P11309 | 2/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.52 |
| ▸ | CDK1 | P06493 | 3/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.52 |
| ▸ | PRKCB | P05771 | 9/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.51 |
| ▸ | PRKCH | P24723 | 3/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565062 | 0.87 | CAMK2D (0.53) | CAMK2DPRKCACCNB2CDK1CCNB1 | |
| SCHEMBL4564848 | 0.80 | PRKCA (0.51) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4559546 | 0.77 | CAMK2D (0.41) | CAMK2DPRKCAPIM1PRKCBGSK3B | |
| SCHEMBL4564844 | 0.70 | CCNB2 (0.58) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL7826797 | 0.70 | PRKCA (0.52) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4684125 | 0.70 | PRKCA (0.62) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL7199461 | 0.69 | PRKACA (0.81) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL7057981 | 0.69 | PRKCA (1.00) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL8154146 | 0.68 | PRKCA (0.98) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL10433663 | 0.68 | PRKCA (0.57) | CAMK2DPRKCAPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608634-B2 | Substituted pyrrolines as kinase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-27 | — | — | US | disclosed |
| US-20070213387-A1 | Substituted pyrrolines as kinase inhibitors | ZHANG HAN-CHENG | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213387-A1 | Substituted pyrrolines as kinase inhibitors | PRKDC, MAP2K2, TTK | CAMK2D 66/4885PRKCA 59/4885PRKACA 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.