Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565202 | 0.90 | CHRM3 (0.41) | CHRM3CCR5EPHX1NOTUMUBE2M | |
| SCHEMBL4503886 | 0.84 | SLC6A2 (0.47) | CACNA1BUBE2MDCUN1D1HSD11B1SLC6A2 | |
| SCHEMBL3961111 | 0.84 | CHRM3 (0.49) | CHRM3CCR5 | |
| SCHEMBL3951844 | 0.84 | CHRM3 (0.49) | CHRM3CCR5 | |
| SCHEMBL3955347 | 0.83 | CHRM3 (0.48) | CHRM3CCR5 | |
| SCHEMBL4497752 | 0.79 | SLC6A2 (0.45) | CACNA1BNOTUMUBE2MDCUN1D1HSD11B1 | |
| SCHEMBL4493804 | 0.79 | SLC6A2 (0.45) | CACNA1BNOTUMUBE2MDCUN1D1HSD11B1 | |
| SCHEMBL4847465 | 0.79 | CHRM3 (0.43) | CHRM3EPHX1NOTUMHSD11B1EPHX2 | |
| SCHEMBL4955085 | 0.79 | CHRM3 (0.43) | CHRM3EPHX1NOTUMHSD11B1EPHX2 | |
| SCHEMBL1566490 | 0.77 | EPHX1 (0.51) | EPHX1NOTUMHSD11B1SLC6A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491723-B2 | Alkanol and cycloalkanol-amine derivatives and methods of their use | WYETH (US) | 2009-02-17 | — | — | US | disclosed |
| US-20050171115-A1 | Alkanol and cycloalkanol-amine derivatives and methods of their use | WYETH (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171115-A1 | Alkanol and cycloalkanol-amine derivatives and methods of their use | FAAH, HTR3A, MAOA | CHRM3 194/4885CCR5 1515/4885CACNA1B 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.