SCHEMBL4565154

SCHEMBL4565154

C=CCc1ccccc1N(c1ccccc1)c1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
MAPT P10636 1/20 0.52
TSHR P16473 2/20 0.34
PSMD14 O00487 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.34
GFER P55789 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
MAOB P27338 4/20 0.32
MAOA P21397 3/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4189715 0.90 GABRA1 (0.40) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL8210128 0.89 CYP3A4 (0.42) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL254011 0.87 GABRA1 (0.36) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL3675862 0.87 GABRA1 (0.40) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL1349623 0.83 ALDH1A1 (0.36) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL11388986 0.80 GABRA1 (0.38) ALDH1A1KDM4EMAPTGABRA1GABRB2
SCHEMBL5485155 0.78 TLR8 (0.33)
SCHEMBL28867129 0.78 GABRA1 (0.40) CYP3A4ALDH1A1L3MBTL1CYP2C19KDM4E
SCHEMBL1369697 0.77 PTGDR2 (0.33) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9
SCHEMBL7006142 0.77 ALDH1A1 (0.77) CYP3A4TDP1ALDH1A1L3MBTL1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants GREAT LAKES CHEMICAL GLOBAL, INC. 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156441-A1 Cycloalkyl phenylenediamines as deposit control agents for lubricants C5, C9, C1S CYP3A4 993/4885TDP1 1337/4885ALDH1A1 1125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.