Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880256 | 0.89 | CYP1A2 (0.49) | CYP1A2ALDH1A1TSHRTDP1NPY5R | |
| SCHEMBL9847486 | 0.87 | GAA (0.39) | CYP1A2ALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL4565156 | 0.85 | ALDH1A1 (0.48) | CYP1A2ALDH1A1HSD17B10ALOX12L3MBTL1 | |
| SCHEMBL9559165 | 0.84 | MAPT (0.44) | CYP1A2ALDH1A1HSD17B10ALOX12L3MBTL1 | |
| SCHEMBL9336222 | 0.83 | ICMT (0.40) | CYP1A2ALDH1A1HSD17B10ALOX12L3MBTL1 | |
| SCHEMBL11032897 | 0.82 | CHKA (0.46) | CYP1A2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL83762 | 0.82 | CHKA (0.46) | CYP1A2ALDH1A1TSHRMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7942696 | 0.80 | CHKA (0.44) | CYP1A2ALDH1A1ALOX12TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL4050783 | 0.80 | CHKA (0.44) | CYP1A2TSHRMEN1KMT2AMAPT | |
| SCHEMBL851567 | 0.79 | CHKA (0.50) | CYP1A2ALDH1A1HSD17B10L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706209-B1 | SUCH AS 2-HYDROXYALKYLACRYLATE, N,N-DIMETHYLAMINOPROPYL METHACRYLAMIDE, N,N-DIETHYLHYDROXYLAMINE AND N-NITROSO-N-PHENYLHYDROXYLAMINE; STORAGE STABLE; HIGH DEGREE OF POLYMERIZATION WITHOUT SEPARATION OF INHIBITOR | ROEHM GMBH & CO. KG (DE) | 2004-03-16 | — | — | US | claimed |
| US-5213699-A | For lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1993-05-25 | — | — | US | claimed |
| EP-0538195-A2 | N-Allyl/benzyl substituted phenylenediamine stabilizers | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | claimed |
| JP-5279304-A | — | — | None | — | — | JP | disclosed |
| JP-63081145-A | — | — | None | — | — | JP | disclosed |
| EP-3680231-A1 | METHOD FOR THE PREPARATION OF N-ISOPROPYL(METH)ACRYLAMIDE | Evonik Operations GmbH (DE) | 2020-07-15 | — | — | EP | disclosed |
| US-10676454-B2 | Method for producing monomers from isomeric mixtures | EVONIK OPERATIONS GMBH (DE) | 2020-06-09 | — | — | US | disclosed |
| EP-2358664-B1 | METHOD FOR PRODUCING N-ISOPROPYL(METH)ACRYLAMIDE | EVONIK OPERATIONS GMBH (DE) | 2020-03-25 | — | — | EP | disclosed |
| US-20190031638-A1 | Method for producing monomers from isomeric mixtures | EVONIK RÖHM GMBH (DE) | 2019-01-31 | — | — | US | disclosed |
| US-9512062-B2 | Method for producing N-isopropyl(meth)acrylamide | EVONIK ROEHM GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20110218312-A1 | METHOD FOR PRODUCING N-ISOPROPYL(METH)ACRYLAMIDE | EVONIK ROEHM GMBH (DE) | 2011-09-08 | — | — | US | disclosed |
| US-4929778-A | PHENYLENEDIAMINE COMPOUNDS, AND HINDERED PHENOLS | BETZ LABORATORIES, INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912247-A | Inhibiting acrylonitrile polymerization | BETZ LABORATORIES, LTD. (US) | 1990-03-27 | — | — | US | disclosed |
| US-4797504-A | HYDROXYLAMINES AND PHENYLENEDIAMINE DERIVATIVES | BETZ LABORATORIES, INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0266906-A2 | Method and composition for inhibiting acrylate ester polymerization | BETZ EUROPE, INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| JP-S6381145-A | RUBBER COMPOSITION CONTAINING ANTIOXIDANT | KAWAGUCHI KAGAKU KOGYO KK | 1988-04-12 | — | — | JP | disclosed |
| US-4720566-A | Method and composition for inhibiting acrylonitrile polymerization | BETZ LABORATORIES, INC. (US) | 1988-01-19 | — | — | US | disclosed |
| EP-0011790-B1 | PROCESS FOR THE PREPARATION OF NITRODIPHENYL AMINE DERIVATIVES | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4238407-A | Process for the preparation of nitro diphenyl amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0011790-A1 | Process for the preparation of nitrodiphenyl amine derivatives | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031638-A1 | Method for producing monomers from isomeric mixtures | GK, ACR, MGLL | CYP1A2 559/4885ALDH1A1 364/4885HSD17B10 125/4885 |
| US-20110218312-A1 | METHOD FOR PRODUCING N-ISOPROPYL(METH)ACRYLAMIDE | ACR, PAM, AMPD2 | CYP1A2 1245/4885ALDH1A1 542/4885HSD17B10 2312/4885 |
| US-10676454-B2 | Method for producing monomers from isomeric mixtures | GK, ACR, MGLL | CYP1A2 559/4885ALDH1A1 364/4885HSD17B10 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.