Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565179 | 1.00 | MTNR1A (0.36) | MTNR1AMTNR1BRAB9AHDAC3HDAC1 | |
| SCHEMBL4551783 | 0.90 | MTNR1B (0.40) | MTNR1AMTNR1BHDAC3HDAC1HDAC2 | |
| SCHEMBL4410486 | 0.72 | HTR2C (0.44) | MTNR1AMTNR1BHTR2CSLC6A3ALDH1A1 | |
| SCHEMBL4423580 | 0.66 | ALDH1A1 (0.41) | MTNR1AMTNR1BRAB9AHTR2CALDH1A1 | |
| Malonic Acid SCHEMBL9222810 | 0.66 | TDP1 (0.48) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL1331551 | 0.66 | TDP1 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL33927 | 0.66 | TDP1 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL1531678 | 0.66 | TDP1 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL33928 | 0.66 | TDP1 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL1330911 | 0.66 | TDP1 (0.56) | ALDH1A1GAAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |