Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 14/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541263 | 0.87 | HPGDS (0.33) | HPGDS | |
| SCHEMBL4565386 | 0.85 | FASN (0.40) | — | |
| SCHEMBL4540383 | 0.78 | HPGDS (0.31) | HPGDS | |
| SCHEMBL4565372 | 0.76 | PIK3C3 (0.36) | — | |
| SCHEMBL4565401 | 0.75 | PIK3CA (0.31) | — | |
| SCHEMBL4541625 | 0.73 | FASN (0.38) | — | |
| SCHEMBL4566498 | 0.72 | FASN (0.42) | HPGDS | |
| SCHEMBL4564364 | 0.68 | HTR6 (0.36) | PDE4B | |
| SCHEMBL15544329 | 0.67 | GRIN1 (0.33) | — | |
| SCHEMBL4565553 | 0.67 | FGFR1 (0.37) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |