Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541263 | 0.75 | HPGDS (0.33) | — | |
| SCHEMBL4565386 | 0.73 | FASN (0.40) | — | |
| SCHEMBL4541625 | 0.71 | FASN (0.38) | — | |
| SCHEMBL4565553 | 0.68 | FGFR1 (0.37) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL4565405 | 0.68 | PTGER3 (0.34) | — | |
| SCHEMBL4540141 | 0.68 | FASN (0.32) | — | |
| SCHEMBL15543527 | 0.67 | FASN (0.30) | — | |
| SCHEMBL4565426 | 0.67 | TGFBR1 (0.38) | LRRK2 | |
| SCHEMBL4564399 | 0.67 | FASN (0.37) | — | |
| SCHEMBL4540383 | 0.66 | HPGDS (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |