Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4564770 | 0.90 | NR3C1 (0.33) | ADRB3ESR1CREBBP | |
| SCHEMBL4565373 | 0.80 | — | — | |
| SCHEMBL4564697 | 0.79 | CHRNA7 (0.33) | ALOX5AP | |
| SCHEMBL15545040 | 0.76 | FFAR4 (0.35) | — | |
| SCHEMBL4565553 | 0.76 | FGFR1 (0.37) | — | |
| SCHEMBL4564893 | 0.74 | FASN (0.35) | — | |
| SCHEMBL15559412 | 0.74 | FFAR4 (0.34) | — | |
| SCHEMBL4564364 | 0.73 | HTR6 (0.36) | — | |
| SCHEMBL4565721 | 0.72 | ALOX5AP (0.32) | ALOX5APFEN1 | |
| SCHEMBL4565577 | 0.71 | SGK1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |