Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 15/20 | 0.34 |
| ▸ | FASN | P49327 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565553 | 0.80 | FGFR1 (0.37) | — | |
| SCHEMBL4564596 | 0.79 | CD74 (0.34) | — | |
| SCHEMBL4565577 | 0.78 | SGK1 (0.46) | — | |
| SCHEMBL4564691 | 0.77 | FASN (0.36) | FASN | |
| SCHEMBL4536541 | 0.76 | — | — | |
| SCHEMBL4565426 | 0.75 | TGFBR1 (0.38) | — | |
| SCHEMBL4564399 | 0.75 | FASN (0.37) | FASN | |
| SCHEMBL4562348 | 0.74 | KDM4E (0.31) | FASN | |
| SCHEMBL4569982 | 0.74 | PTPN1 (0.39) | FASN | |
| SCHEMBL4565379 | 0.73 | IRAK4 (0.34) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637660-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012064642-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-05-18 | — | — | WO | disclosed |