Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914280 | 0.84 | ALDH1A1 (0.55) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL3317320 | 0.84 | ALDH1A1 (0.55) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL979842 | 0.82 | CA12 (0.58) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL27357244 | 0.82 | ALDH1A1 (0.53) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL5403782 | 0.81 | CA12 (0.56) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL5404802 | 0.81 | ALDH1A1 (0.52) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL10935027 | 0.81 | ALDH1A1 (0.52) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL4799007 | 0.79 | ALDH1A1 (0.50) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL9617692 | 0.79 | ALDH1A1 (0.50) | HPGDKDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL30874084 | 0.79 | WDR5 (0.51) | HPGDKDM4EHSD17B10ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2007149782-A2 | SELECTIVE INHIBITORS FOR TRANSFERASES | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306201-A1 | SELECTIVE INHIBITORS FOR TRANSFERASES | TYMP, PCNA, TK1 | HPGD 1089/4885KDM4E 1337/4885HSD17B10 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.