Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963518 | 0.79 | SCD (0.48) | HPGDSALKBH2HDAC3HDAC8NAMPT | |
| SCHEMBL19252949 | 0.79 | SCD (0.55) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18704475 | 0.78 | CYP17A1 (0.42) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29435026 | 0.77 | HDAC3 (0.58) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL222876 | 0.77 | HDAC3 (0.58) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL22570944 | 0.76 | NOTUM (0.50) | KEAP1CYP17A1HDAC3HDAC1HDAC2 | |
| SCHEMBL7439456 | 0.76 | HDAC3 (0.57) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3510402 | 0.74 | CYP17A1 (0.67) | CYP17A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6165168 | 0.74 | HPGDS (0.61) | KEAP1NFE2L2HPGDSALKBH2EGLN1 | |
| SCHEMBL29029431 | 0.74 | HDAC3 (0.56) | CYP17A1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |