Styrene

Styrene

SCHEMBL4565859

C=CCN(CC=C)CCOC(=O)C(=C)C.C=CCOC(=O)C(=C)C.C=Cc1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.47
KMT2A Q03164 7/20 0.47
MEN1 O00255 4/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 8/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 2/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP3A4 P08684 1/20 0.37
ALOX12 P18054 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4565155 0.93 KDM4E (0.44) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
Styrene SCHEMBL88055 0.86 MEN1 (0.50) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL719482 0.86 THRB (0.41) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
Styrene SCHEMBL8106633 0.85 MEN1 (0.47) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
Styrene SCHEMBL3025658 0.84 LMNA (0.50) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
Styrene SCHEMBL4287862 0.84 MEN1 (0.48) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1
Styrene SCHEMBL446411 0.81 CHRM1 (0.43) SMN1; SMN2ALDH1A1TDP1LMNATSHR
Styrene SCHEMBL11131494 0.81 BCHE (0.46) KMT2AMEN1SMN1; SMN2ALDH1A1TDP1
Styrene SCHEMBL8361059 0.81 THRB (0.47) KDM4EKMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL505741 0.81 THRB (0.46) KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US claimed
US-7632620-B2 Coated carrier XEROX CORPORATION (US) 2009-12-15 US disclosed
US-7452650-B2 Coated carriers and processes thereof XEROX CORPORATION (US) 2008-11-18 US disclosed
US-7374850-B2 Coated carriers XEROX CORPORATION (US) 2008-05-20 US disclosed
US-7374849-B2 Coated carrier XEROX CORPORATION (US) 2008-05-20 US disclosed
US-20060246369-A1 Coated carriers XEROX CORPORATION 2006-11-02 US disclosed
US-20060172218-A1 Coated carrier XEROX CORPORATION 2006-08-03 US disclosed
EP-1686428-A1 Coated carrier Xerox Corporation (US) 2006-08-02 EP disclosed
US-20060166124-A1 Coated carriers and processes thereof XEROX CORPORATION 2006-07-27 US disclosed
US-20060166125-A1 Coated carrier XEROX CORPORATION 2006-07-27 US disclosed
US-6132917-A Coated carrier XEROX CORPORATION (US) 2000-10-17 US disclosed
US-6051353-A REACTION PRODUCT OF GLYCIDYL METHACRYLATE POLYMER WITH AMINOALKYL OR (AMINOALKYL)AMINOALKYL METHACRYLATE POLYMER XEROX CORPORATION (US) 2000-04-18 US disclosed
US-6051354-A MIXING IN A HIGH SHEAR DEVICE A CARRIER CORE AND A CARRIER COATING, AND WHEREIN SAID HIGH SHEAR DEVICE CONTAINS IMPELLERS. XEROX CORPORATION (US) 2000-04-18 US disclosed
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US disclosed
US-6042981-A Coated carrier XEROX CORPORATION (US) 2000-03-28 US disclosed
US-6037091-A Carrier with ferrocene containing polymer XEROX CORPORATION (US) 2000-03-14 US disclosed
US-6010812-A Coated carrier XEROX CORPORATION (US) 2000-01-04 US disclosed
US-6004712-A CORE AND THEREOVER A POLYMER OF (1) METHYLMETHACRYLATE AND A MONOALKYL AMINOALKYL METHACRYLATE, OR (2) A POLYMER OF METHYLMETHACRYLATE AND DIALKYLAMINOALKYL METHACRYLATE, TONER AND DEVELOPER XEROX CORPORATION (US) 1999-12-21 US disclosed
US-5945244-A Coated carrier XEROX CORPORATION (US) 1999-08-31 US disclosed
US-5935750-A A CARRIER COMPOSED OF A CORE AND A COATING OF A POLYMER CONTAINING QUTERNARY AMMONIUM SALT GROUP AND CONTAINS A CONDUCTIVE COMPONENT XEROX CORPORATION (US) 1999-08-10 US disclosed