Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19092267 | 0.81 | PRMT3 (0.33) | — | |
| SCHEMBL24449206 | 0.79 | — | — | |
| SCHEMBL20991844 | 0.79 | — | — | |
| SCHEMBL20206099 | 0.79 | — | — | |
| SCHEMBL27650379 | 0.72 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL19191760 | 0.71 | CHRNB2 (0.37) | SIGMAR1 | |
| SCHEMBL16099448 | 0.70 | — | — | |
| SCHEMBL24406565 | 0.70 | — | — | |
| SCHEMBL20354356 | 0.70 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL24700034 | 0.70 | FDPS (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125816-A2 | METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY | Alantos Pharmaceuticals Holding, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008109177-A2 | METALLOPROTEASE INHIBITORS CONTAINING A HETEROCYCLIC MOIETY | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-09-12 | — | — | WO | disclosed |