Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4777090 | 0.82 | ELANE (0.45) | NOS1ALDH1A1TSHRELANE | |
| Hydrochloric Acid SCHEMBL3817658 | 0.82 | ELANE (0.45) | NOS1ALDH1A1TSHRELANE | |
| SCHEMBL19436518 | 0.80 | NOS1 (0.36) | NOS1KMT2AF2ELANE | |
| SCHEMBL4259465 | 0.78 | NOS1 (0.56) | NOS1L3MBTL1TSHRTDP1 | |
| SCHEMBL20745704 | 0.77 | NOS1 (0.45) | NOS1ELANE | |
| SCHEMBL21995202 | 0.73 | THRB (0.46) | KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL4366139 | 0.73 | ALDH1A1 (0.48) | KMT2ABCHEALDH1A1L3MBTL1TSHR | |
| SCHEMBL164431 | 0.71 | KMT2A (0.52) | KMT2AF2ALOX15BCHEALDH1A1 | |
| SCHEMBL29991043 | 0.71 | KMT2A (0.52) | KMT2AF2ALOX15BCHEALDH1A1 | |
| SCHEMBL4748490 | 0.71 | KMT2A (0.52) | NOS1KMT2AF2ALOX15BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2131655-A2 | TRI-ARYL/HETEROAROMATIC CANNABINOIDS AND USE THEREOF | The University of Tennessee Research Foundation (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008109027-A2 | TRI-ARYL/HETEROAROAROMATIC CANNABINOIDS AND USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2008-09-12 | — | — | WO | disclosed |